The Three-City Study

   

Les publications scientifiques de l’étude des Trois Cités

2002
Alpérovitch A, Amouyel P, Dartigues JF, Ducimetière P, Mazoyer B, Ritchie K, Tzourio C. Epidemiological studies on aging in France: from the PAQUID study to the Three-City study. C R Biol. 2002;325(6):665-72. Review. French

2003

The 3C Study Group. Vascular factors and risk of dementia. Design of the Three-City Study and baseline characteristics of the study population. Neuroepidemiology. 2003; 22:316-325.

2004

Larrieu S, Letenneur L, Berr C, Dartigues JF, Ritchie K, Alpérovitch A, Tavernier B, Barberger-Gateau P. Sociodemographic differences in dietary habits in a population-based sample of elderly subjects in the 3C Study. J Nutr Health Aging 2004; 8:497-502.

 

Larrieu S, Pérès K, Letenneur L, Berr C, Dartigues JF, Ritchie K, Février B, Alpérovitch A, Barberger-Gateau P. Relationship between body mass index and different domains of disability in older persons: The 3C Study. Int J Obes Relat Metab Disord 2004; 28:1555-60.

Ritchie K, Artero S, Beluche I, Ancelin ML, Mann A, Dupuy AM, Malafosse A, Boulenger JP. Prevalence of DSM-IV psychiatric disorder in the French elderly population. Br J Psychiatry. 2004 Feb;184:147-52. (Esprit cohort, subgroup of Montpellier 3C).

 

Zureik M, Gariépy J, Courbon D, Dartigues JF, Ritchie K, Tzourio C,
Alpérovitch A, Simon A, Ducimetière P. Alcohol consumption and large artery structure in older French adults. The Three-City Study. Stroke 2004; 35:2770-2775.

2005

Barberger-Gateau P, Jutand MA, Letenneur L, Larrieu S, Berr C, Tavernier B and the Three-City Study Investigators. Correlates of regular fish consumption in French elderly community dwellers: data from the Three-City study. Eur J Clin Nutrition 2005; 59:817-825.

 

Cowppli-Bony P, Fabrigoule C, Letenneur et al. Validity of the five-word screening test for Alzheimer’s disease in a population-based study. Rev Neurol (Paris) 2005; 161:1205-1212.

 

De Bisschop C, Marty ML, Tessier JF, Barberger-Gateau P, Dartigues JF, Guénard H. Expiratory flow limitation and obstruction in the elderly. Eur Respir J 2005; 26:594-601.

 

Dufouil C*, Richard F*, Fiévet N, Dartigues JF, Ritchie K, Tzourio C, Amouyel P, Alpérovitch A. APOE genotype, cholesterol level, lipid-lowering treatment and dementia. The Three-City Study. Neurology 2005; 64:1531-1538.

 

Elbaz A, Ripert M, Tavernier B, Février B, Zureik M, Gariépy J, Alpérovitch A, Tzourio C. Common carotid artery intima-media thickness, carotid plaques, and walking speed. Stroke 2005; 36:2198-2202.

Feart C, Pallet V, Boucheron C, Higueret D, Alfos S, Letenneur L, Dartigues JF, Higueret P. Aging affects the retinoic acid and the triiodothyronine nuclear receptor mRNA expression in human peripheral blood mononuclear cells.Eur J Endocrinol 2005 Mar;152(3):449-58.

 

Lechevallier-Michel N, Gautier-Bertrand M, Alpérovitch A, Berr C, Belmin J, Legrain S, Saint-Jean O, Tavernier B, Dartigues JF, Fourrier-Régalat A. Frequency and risk factors of potentially inappropriate medication use in a French community-dwelling elderly population: Results from the 3C Study. Eur J Clin Pharmacol 2005; 60:813-819.

2006

Artero S, Astruc B, Courtet P, Ritchie K. Life-time history of suicide attempts and coronary artery disease in a community-dwelling elderly population. International Journal of Geriatric Psychiatry 2006; 21:108-112.

 

Brindel P, Hanon O,  Dartigues JF, Ritchie K, Lacombe JM, Alpérovitch A, Tzourio C for the 3C Study investigators. Prevalence, awareness, treatment and control of hypertension in the elderly. The Three-City Study. J Hypertension 2006; 24:51-58.

 

Debette S, Lambert JC, Gariépy J, Fievet N, Tzourio C, Dartigues JF, Ritchie K, Dupuy AM, Alpérovitch A, Ducimetière P, Amouyel P, Zureik M. New insight into the association of apoE genetic variants with carotid plaques and intima-media thickness. Stroke 2006; 37:2917-2923.

 

Harrabi I, Rondeau V, Dartigues JF et al. Effects of particulate air pollution on systolic blood pressure:A population-based approach. Environ Res 2006; 101:89-93.

 

Soumaré A, Elbaz E, Ducros V, Tavernier B, Alpérovitch A ,Tzourio C. Homocysteine and the motor function in the elderly – The Three-City Study. Neurology 2006; 67:285-290.

2007

Amieva H, Carcaillon L, Rouze L'Alzit-Schuermans P, Millet X, Dartigues JF, Fabrigoule C. Cued and uncued memory tests: norms in elderly adults from the 3 Cities epidemiological study.Rev Neurol (Paris). 2007;163(2):205-21. French


Barberger-Gateau P, Raffaitin C, Letenneur L, Berr C, Tzourio C, Dartigues JF, Alpérovitch A. Dietary patterns and risk of dementia: the Three-City cohort study. Neurology 2007; 69:1921-1930.

 

Bourdel-Marchasson I, Helmer C, Barberger-Gateau P, Peuchant E, Février B, Ritchie K, Dartigues JF. Characteristics of undiagnosed diabetes in community dwelling French elderly: The 3C study. Diabetes Research and Clinical Practice 2007; 76:257-264.

 

Empana JP, Zureik M, Gariépy J, Courbon D, Dartigues JF, Ritchie K, Tzourio C, Alpérovitch A, Ducimetière P. Metabolic syndrome and carotid artery structure in non-institutionalized elderly subjects-The Three-City Study. Stroke 2007; 38:893-899.

 

Feart C, Jutand MA, Larrieu S, Letenneur L, Delcourt C, Combe C, Barberger-Gateau P. Energy, macronutrient and fatty acid intake of French elderly community dwellers and association with socio-demographic characteristics: data from the 3C-Bordeaux sample of the Three-City Study. Br J Nutrition 2007; 98:1046-1057.

 

Godin O, Dufouil C, Ritchie K, Dartigues JF, Tzourio C, Alpérovitch A. Depressive symptoms, major depressive episode and cognition il the elderly: the Three-City Study. Neuroepidemiology 2007; 28:101-108.

 

Ritchie K, Carrière I, Portet F, de Mendoca A, Dartigues JF, Rouaud 0, Barberger-Gateau P, Ancelin, ML. The neuroprotective effect of caffeine: a prospective population study (The Three City Study). Neurology 2007; 69:536-545.

 

Tsuno N, Jaussent I, Dauvilliers Y, Touchon J, Ritchie K, Besset A. Determinants of excessive daytime sleepiness in a French community-dwelling population.  J Sleep Res 2007; 16:364-371.

2008

Artero S, Ancelin M-L, Portet F, Dupuy ,  Berr C , Dartigues J-F, Tzourio C, Rouaud O, Poncet M, Pasquier F , Auriacombe S, Touchon J, Ritchie K . Risk profiles for Mild Cognitive Impairment and progression to dementia are gender specific. Journal of Neurology, Neurosurgery and Psychiatry 2008; 79:979-984.

 

Avila-Funes JA, Helmer C, Amieva H, Barberger-Gateau P, Le Goff M, Ritchie K, Portet F, Carrière I, Tavernier B, Gutrtiérez-Robledo LM, Dartigues, JF. Frailty among community-dwelling elderly people in France: the three-city study. J Gerontol A Biol Sci Med Sci 2008; 63:1089-1096

Ben Salem D, Walker PM, Aho S, Tavernier B, Giroud M, Tzourio C, Ricolfi F, Brunotte F. Brain flexibility and balance and gait performances mark morphological and metabolic abnormalities in the elderly. J Clin Neurosci. 2008 Dec;15(12):1360-5. Epub 2008 Oct 26

 

Ben Salem D, Walker PM, Bejot Y, Aho SL, Tavernier B, Rouaud O, Ricolfi F, Brunotte F. N-acetylaspartate/creatine and choline/creatine ratios in the thalami, insular cortex and white matter as markers of hypertension and cognitive impairment in the elderly. Hypertens Res. 2008;31(10):1851-7

 

Bruandet A, Richard F, Tzourio C, Berr C, Dartigues Jf, Alperovitch A, Amouyel P, Helbecque N. Haplotypes across ACE and the risk of Alzheimer disease. The Three-City Study. J Alz Disease 2008; 13:333-339.

 

Chaudieu I*, Beluche I*, Norton J, Boulenger JP, Ritchie K, Ancelin ML. Abnormal reactions to environmental stress in elderly persons with anxiety disorders:evidence from a population study of diurnal cortisol changes.  Journal of Affective Disorders 2008; 106:307-313.

 

Debette S, Courbon D, Leone N, Gariépy J, Tzourio C, Dartigues JF, Barberger-Gateau P, Ritchie K, Alpérovitch A, Amouyel P, Ducimetière P, Zureik M. Tea consumption is inversely associated with carotid plaques in women. Arterioscl Thromb Vasc Biol 2008; 28:353-359.

 

Debette S, Leone N, Courbon D, Gariépy J, Tzourio C, Dartigues JF, Ritchie K, Alpérovitch A, Ducimetière P, Amouyel P, Zureik M. Calf circumference is inversely associated with carotid plaques. Stroke 2008; 39:2958-2965

 

Dupuy AM, Carrière I, Scali J, Cristol JP, Ritchie K, Dartigues JF, Gambert P, Ancelin ML. Lipid levels and cardiovascular risk in elderly women:a general population study of the effects of hormonal treatment and lipid-lowering agents. Climacteric 2008; 11:74-83.

 

Feart C, Peuchant E, Letenneur L, Samieri C, Montagnier D, Fourrier-Reglat A, Barberger-Gateau P. Plasma eicosapentaenoic acid (EPA) is inversely associated with severity of depressive symptomatology in the elderly: data from the Bordeaux sample of the Three-City study. American Journal of Clinical Nutrition 2008; 87:1156-1162.

 

Godin O, Dufouil C, Maillard P, Delcroix N, Mazoyer B, Crivello F, Alpérovitch A, Tzourio C. White matter lesions as a predictor of depression in the elderly- The 3C-Dijon study. Biological Psychiatry 2008; 63:663-669.

 

Helmer C, Pérès K, Pariente A, Pasquier F, Auriacombe S, Poncet M, Portet F, Rouaud O, Ritchie K, Tzourio C, Dartigues JF. Primary and secondary care consultations in elderly demented individuals in France. Results from the Three-City Study. Dement Geriatr Cogn Disord. 2008; 26(5):407-15.

 

Helmer C, Bricout H, Gin H, Barberger-Gateau P. Macronutrient intake and discrepancy with nutritional recommendations in a group of elderly diabetic subjects. Br J Nutr. 2008; 99:632-638.

 

Lafont S, Laumon B, Helmer C, Dartigues JF, Fabrigoule C. Driving cessation and self-reported car crashes in older drivers: the impact of cognitive impairment and dementia in a population-based study. J Geriatr Psychiatry Neurology 2008; 21:171-182.

 

Larrieu S, Carcaillon L, Lefranc A, Helmer C, Dartigues JF, Tavernier B, Ledrans M, Filleul M. Factors associated with morbidity during the 2003 heat wave in two population-based cohort of elderly subjects:PAQUID and the Three-City Study.  Eur J Epidemiol 2008; 23:295-302.

 

Lenoir H, Lacombe JM, Dufouil C, Ducimetière P, Hanon O, Ritchie K, Dartigues JF, Alpérovitch A, Tzourio C. Relationship between blood pressure and depression in the elderly. The Three-City (3C) Study. J Hypertension 2008; 26:1765-1772.

 

Leone N , Ducimetière P, Gariépy J, Courbon D, Tzourio C, Dartigues JF, Tzourio C, Alpérovitch A, Amouyel P, Safar ME, Zureik M. Distension of carotid artery and risk of coronary events – The Three-City study. Arterioscl Thromb Vasc Biol 2008; 1392-1397.

 

Maillard P,  Delcroix N, Crivello F, Dufouil C, Gicquel S, Joliot M, Tzourio-Mazoyer N, Alpérovitch A, Tzourio C,  Mazoyer M. An automated procedure for the assessment of white matter hyperintensities on multispectral (T1, T2, PD) MRI and its between-centre reproducibility evaluation on two large community databases. Neuroradiology 2008; 50:31-42.

Ryan J, Carrière I, Ritchie K, Stewart R, Toulemonde G, Dartigues JF, Tzourio C, Ancelin ML. Late-life depression, gender and mortality:the influence of gender and antidepressant use. British J Psychiatry 2008; 192:10-18.

 

Ryan J, Carrière I., Scali J. Ritchie K. and Ancelin M.L.  Lifetime hormonal factors may predict late-life depression in women. International Psychogeriatrics 2008; 20:1203-1218.

 

Samieri C, Féart C, Letenneur L, Dartigues J-F, Pérès K,  Auriacombe S, Peuchant E, Delcourt C, Barberger-Gateau P. Low plasma eicosapentaenoic acid (EPA) and depressive symptomatology are independent predictors of dementia risk. American Journal of Clinical Nutrition 2008; 88: 714-721.

 

Samieri C, Jutand MA, Féart C,  Capuron L, Letenneur L, Barberger-Gateau P. Dietary patterns derived by hybrid clustering method in older persons: association with cognition, mood and self-rated health. Journal of the American Dietetic Association 2008; 108(9):1461-1471.

 

Soudry A, Dufouil C, Ritchie K, Dartigues JF, Tzourio C, Alpérovitch A. Factors associated with change in antidepressant use in a community-dwelling elderly cohort. Eur J Clin Pharmacol 2008; 64:51-59.

 

Soudry A, Dufouil C, Ritchie K, Dartigues JF, Tzourio C, Alpérovitch A. Factors associated with antidepressant use in depressed and non depressed community-dwelling elderly. Int J Geriatr Psychiatry 2008; 23: 324-30.

   

Stewart R, Dufouil C, Godin O, Ritchie K, Maillard P, Delcroix N, Crivello F, Mazoyer B, Tzourio C. Neuroimaging correlates of subjective memory deficits in a community population. Neurology 2008; 70:1601-1607.

 

Vidal JS, Dufouil C, Ducros V, Tzourio C. Homocysteine, Folate and Cognition in a Large Community-Based Sample of Elderly People - The 3C Dijon Study. Neuroepidemiology 2008; 30:207-214.

2009

Akbaraly TN, Portet F, Fustinoni S, Dartigues JF, Artero S, Rouaud O, Touchon J, Ritchie K, Berr C..  Leisure activity and risk of dementia: results from the Three-City Study. Neurology2009; 73:854-61

 

Alpérovitch A, Lacombe JM, Hanon O, Dartigues JF, Ritchie K, Ducimetière P, Tzourio C. Relation of blood pressure and outdoor temperature in large sample of elderly individuals. Archives of Internal Medecine 2009; 169:75-80

 

Alpérovitch A, Bertrand M, Jougla E, Vidal JS, Ducimetière P, Helmer C, Ritchie K, Pavillon G, Tzourio C. Do we really know the cause of death of the very old ? Comparison between official mortality statistics and cohort study classification. Eur J Epidemiol. 2009; 24:669-675]

 

Avila-Funes JA, Amieva H, Barberger-Gateau P, Le Goff M, Raoux N, Ritchie K, Carriere I, Tavernier B, Tzourio C, Gutierrez-Robledo LM, Dartigues JF. Cognitive Impairment Improves the Predictive Validity of the Phenotype of Frailty for Adverse Health Outcomes: The Three-City Study. Journal of the American Geriatrics Society 2009; 57:453-61.

 

Beluche I*, Chaudieu*, Norton J, Carrière I, Boulenger JP, Ritchie K, Ancelin ML. Persistence of abnormal cortisol levels in elderly depressed persons after recovery from major depression. Journal of Psychiatric Research 2009; 43:773-783


Berdot S, Bertrand M, Dartigues JF, Fourrier A, Tavernier B, Ritchie K, Alpérovitch A. Inappropriate medication use and risk of falls – a prospective study in a large community-dwelling elderly cohort. BMC Geriatr. 2009 Jul 23 9: 30.

 

Berr C, Portet F, Carriere I, Akbaraly T, Feart C, Gourlet V, Combe N, Barberger-Gateau P, Ritchie K. Olive oil and cognition: the Three-City cohort study. Dem Ger Cog Dis 2009; 28; 357-364

 

Bineau S, Dufouil C, Helmer C, Ritchie K, Empana JP, Ducimetière P, Alpérovitch A, Bousser MG, Tzourio C. Framingham stroke risk function in a large population-based cohort of elderly people: the 3C Study. Stroke 2009; 40:1564-1570

 

Buyck JF, Dufouil C, Ducimetière P, Alpérovitch A, Bousser MG, Kurth T, Tzourio C. Cerebral white matter lesions are associated with the risk of stroke but not with other vascular events. The 3C-Dijon Study. Stroke 2009; 40:2327-2331

 

Capuron L, Moranis A, Combe N, Cousson-Gélie F, Fuchs D, De Smedt-Peyrusse V, Barberger-Gateau P, Layé S. Vitamine E status and quality of life in the elderly: influence of inflammatory processes. Br J Nutrition 2009; 102:1390-94


Carcaillon L, Amieva H, Auriacombe S, Helmer C, Dartigues JF. A subtest of the MMSE as a valid test of episodic memory? Comparison with the Free and Cued Reminding Test. Dement Geriatr Cogn Disord. 2009; 27:429-38.

 

Carcaillon L, Gaussem P, Ducimetière P, Giroud M, Ritchie K, Scarabin PY. Elevated plasma fibrin D-dimer as a risk factor for vascular dementia: the Three-City cohort study. J Throm Haemost 2009; 7:1912-8


Carrière I., Fourrier-Reglat A., Dartigues J-F., Rouaud O., Pasquier F., Ritchie K. and Ancelin M.L. Drugs with anticholinergic properties, cognitive decline and dementia in an elderly general population (The Three City Study). Arch Intern Med 2009; 169:1317-24

 

Chapuis J, Hot D, Hansmannel F, Kerdraon O, Ferreira S, Hubans C, Maurage CA, Huot L, Bensemain F, Laumet G, Ayral AM, Fiévet N, Hauw JJ, DeKosky ST, Lemoine Y, Iwatsubo T, Wavrabt-Devrièze F, Dartigues JF, Tzourio C, Buée L, Pasquier F, Berr C, Mann D, Lendon C, Alpérovitch A, Kamboh Mi, Amouyel P, Lambert JC. Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer’s disease. Molecular Psychiatry 2009; 14:1004-16

 

Debette S, Bevan S, Dartigues JF, Sitzer M, Lorenz M, Ducimetière P, Amouyel P, Markus HS. Fractalkine receptor/ligand genetic variants and carotid intima-media thickness. Stroke 2009; 40:2212-4

 

Dumurgier J, Elbaz A, Ducimetière P, Tavernier B, Alpérovitch A, Tzourio C. Slow walking speed and cardiovascular death in well functioning older adults: prospective cohort study. BMJ 2009; 339:

 

Empana JP, Dauvilliers Y, Dartigues JF, Ritchie K, Gariepy J, Jouven X, Tzourio C, Amouyel P, Besset A, Ducimetière P. Excessive daytime sleepiness is an independent risk factor for cardiovascular mortality in community-dwelling elderly. The Three-City Study. Stroke 2009; 40:1219-1224

 

Féart C, Samieri  C, Rondeau V, Amiéva H, Portet F, Dartigues JF, Scarmeas N, Barberger-Gateau P. Adherence to the Mediterranean Diet, Cognitive Decline and Risk of Dementia. JAMA, 2009; 302:638-48

 

Godin O, Maillard P, Crivello F, Alpérovitch A, Mazoyer B, Tzourio C, Dufouil C. Hippocampal atrophy, whole brain volumes and white matter lesions. The 3C-Dijon MRI study. Cerebrovasc Dis 2009; 28:2327-31

 

Godin O, Tzourio C,  Maillard P, Alpérovitch A,  Mazoyer B, Dufouil C.  Apolipoprotein E genotype is related to progression of white matter lesions load. Stroke 2009; 40:3186-90

 

Isaac V, Stewart R, Artero S, Ancelin M-L, Ritchie K. Social activity and improvement in depressive symptoms in the elderly: a prospective community cohort study. Am  J Geriatric Psychiatry 2009; 17:688-696

Lachouri M, Gourlet V, D'Athis P, Tzourio C, Quantin C. Changes in blood pressure in a large cohort of elderly individuals: Study 3C. Arch Cardiovasc Dis. 2009;102(2):127-34. Epub 2009 Feb 12.

 

Lambert JC, Schraen-Maschke S, Richard F, Fievet N, Rouaud O, Berr C, Dartigues J-F, Tzourio C, Alpérovitch A, Buée L, Amouyel P. Association of plasma Aβ with risk of dementia : the prospective 3C-study. Neurology 2009; 73:847-853

 

Lambert JC, Heath S, Even G, Campion D, Sleegers K, Hiltunen M, Combarros O, Zelenika D, Bullido MJ, Tavernier B, Letenneur L, Bettens K, Berr C, Pasquier F, Fiévet N, Barberger-Gateau P, Engelborghs S, De Deyn P, Mateo I, Franck A, Helisalmi S, Porcellini E, Hanon O; the European Alzheimer's Disease Initiative Investigators, de Pancorbo MM, Lendon C, Dufouil C, Jaillard C, Leveillard T, Alvarez V, Bosco P, Mancuso M, Panza F, Nacmias B, Bossù P, Piccardi P, Annoni G, Seripa D, Galimberti D, Hannequin D, Licastro F, Soininen H, Ritchie K, Blanché H, Dartigues JF, Tzourio C, Gut I, Van Broeckhoven C, Alpérovitch A, Lathrop M, Amouyel P. Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer’s disease. Nat Genet. 2009;41:1094-1099

 

Noize P., Bazin F., Dufouil C., Lechevallier-Michel N., Ancelin M.L, Dartigues J.F., Tzourio C., Moore N. and Fourrier-Réglat A. Comparison of health insurance claims and patient interviews in assessing drug use: data from the Three-City Study. Pharmacoepidemiology and Drug Safety, 2009; 18(4):310-9.

 

Maillard P, Crivello F, Dufouil C, Tzourio-Mazoyer N, Tzourio C and Mazoyer B. Longitudinal follow-up of individual white matter hyperintensities in a large cohort of healthy elderly . Neuroradiology 2009; 51:209-220

 

Raffaitin C, Gin H, Empana JP, Helmer C, Berr C, Tzourio C, Portet F, Dartigues JF, Alperovitch A, Barberger-Gateau P. Metabolic syndrome and risk for incident Alzheimer's disease and vascular dementia: the three-city study. Diabetes Care. 2009: 32:169-74

 

Ritchie K*, Jaussent I *, Stewart R, Dupuy AM, Courtet P, Ancelin ML, Malafosse A. Adverse childhood environment and late-life depression. Journal of Clinical Psychiatry 2009; 70:1281-88

 

Ryan J, Carrière I, Scali J, Ritchie K, Ancelin ML. Life-time estrogen exposure and cognitive functioning in later life. Psychoneuroendocrinology, 2009; 34:287-298

 

Ryan J, Carrière I, Scali J, Dartigues JF, Tzourio C, Ritchie K, Ancelin ML. Characteristics of hormone therapy and the association with cognitive function and dementia: the prospective Three City Study. Neurology 2009; 73:1729-37

Scali J, Ryan J, Carrière I, Ritchie K, Ancelin ML. A prospective study of hormonal treatment and anxiety disorders in community-dwelling elderly women (the Esprit Study). J Affect Disord. 2009 May;115(1-2):274-9. Epub 2008 Oct 11.

 

Soumaré A, Elbaz A, Zhu Y, Maillard P, Crivello F, Tavernier B, Dufouil C, Mazoyer B, and Tzourio C. White matter lesions volume and motor performances in the elderly. Ann Neurol2009; 65: 706-15

 

Soumaré A, Tavernier B, Alpérovitch A, Tzourio C, Elbaz. A cross-sectional and longitudinal study of the relation between walking speed and cognitive function in community-dwelling elderly people. Journal of Gerontology: Medical Sciences 2009; 64:1058-65

2010

Akbaraly TN, Kivimaki M, Ancelin ML, Barberger-Gateau P, Mura T, Tzourio C, Touchon J, Ritchie K, Berr C. Metabolic syndrome, its components, and mortality in the elderly. J Clin Endocrinol Metab 2010 Nov; 95(11):E327-32. Epub 2010 Sep 1.

 

Ancelin ML, Carrière I, Boulenger JP, Malafosse A, Stewart R, Cristol JP, Ritchie K, Chaudieu I, Dupuy AM. Gender and genotype modulation of the association between lipid levels and depressive symptomatology in community-dwelling elderly (the ESPRIT study). Biol Psychiatry. 2010 Jul 15;68(2):125-32. Epub 2010 May 26.

Auriacombe S, Helmer C, Amieva H, Berr C, Dubois B, Dartigues JF. Validity of the free and cued selective reminding test in predicting dementia: the 3C study. Neurology 2010; 74:1760-7.

 

Beluche I, Carrière I, Ritchie K Ancelin ML. A prospective study of diurnal cortisol and cognitive function in community-dwelling elderly people. Psychological Medicine 2010; 40:1039-1049

 

Bentayeb M, Helmer C, Raherison C, Dartigues JF, Tessier JF, Annesi-Maesano I. Bronchitis-like symptoms and proximity air pollution in French elderly. Respir Med 2010; 104(6): 880-8. Epub 2010 Feb 2.PMID: 20129767

 

Bonaventure A, Kurth T, Pico F, Barberger-Gateau P, Ritchie K, Stapf C, Tzourio C. Serum triglycerides and the risk of hemorrhagic stroke vs. ischemic vascular events: the Three-City Study. Atherosclerosis 2010; 30:159-167

 

Crivello F, Lemaître H, Dufouil C, Grassiot B, Delcroix N, Tzourio-Mazoyer N, Tzourio C, Mazoyer B. Effects of ApoE-epsilon4 allele load and age on the rates of grey matter and hippocampal volumes loss in a longitudinal cohort of 1186 healthy elderly persons. Neuroimage 2010; 53(3): 1064-9.

 

Debette S, Bis JC, Fornage M, Schmidt H, Ikram MA, Sigurdsson S, Heiss G, Struchalin M, Smith AV, van der Lugt A, DeCarli C, Lumley T, Knopman DS, Enzinger C, Eiriksdottir G, Koudstaal PJ, DeStefano AL, Psaty BM, Dufouil C, Catellier DJ, Fazekas F, Aspelund T, Aulchenko YS, Beiser A, Rotter JI, Tzourio C, Shibata DK, Tscherner M, Harris TB, Rivadeneira F, Atwood LD, Rice K, Gottesman RF, van Buchem MA, Uitterlinden AG, Kelly-Hayes M, Cushman M, Zhu Y, Boerwinkle E, Gudnason V, Hofman A, Romero JR, Lopez O, van Duijn CM, Au R, Heckbert SR, Wolf PA, Mosley TH, Seshadri S, Breteler MM, Schmidt R, Launer LJ, Longstreth WT Jr. Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium. Stroke 2010; 41(2): 210-7

 

Delcourt C, Korobelnik JF, Barberger-Gateau P, Delfyer MN, Rougier MB, Le Goff  M, Malet F, Colin J, Dartigues JF. Nutrition and age-related eye diseases : the  ALIENOR (antioxydants, lipides essentiels, nutrition et maladies oculaires) study. J Nutr Health Aging 2010 ; 14 :854-61 (the ALIENOR study is conducted in a sub-group of the 3C-Bordeaux cohort.)

 

Dumurgier J, Elbaz A, Dufouil C, Tavernier B, Tzourio C Hypertension and lower walking speed in the elderly: the Three-City study. J Hypertens 2010; 28(7):1506-14.

 

Féart C, Siewe A, Samieri C, Peuchant E, Helmer C, Alfos S, Pallet V, Barberger-Gateau P. Plasma retinol and association with socio-demographic and dietary characteristics of free-living older persons: the Bordeaux sample of the three-city study. Int J Vitam Nutr Res 2010; 80:32-44

Féart C, Samieri C, Barberger-Gateau P. Mediterranean diet and cognitive function in older adults. Curr Opin Clin Nutr Metab Care. 2010 Jan;13(1):14-8.

 

Godin O, Tzourio C, Rouaud O, Zhu Y, Maillard P, Pasquier F, Crivello F, Alpérovitch A, Mazoyer B, Dufouil C. Joint effect of white matter lesions and hippocampal volumes on severity of cognitive decline: the 3C-Dijon MRI study. J Alzheimers Dis 2010; 20(2):453-63.

 

Lambert JC, Sleegers K, González-Pérez A, Ingelsson M, Beecham GW, Hiltunen M, Combarros O, Bullido MJ, Brouwers N, Bettens K, Berr C, Pasquier F, Richard F, Dekosky ST, Hannequin D, Haines JL, Tognoni G, Fiévet N, Dartigues JF, Tzourio C, Engelborghs S, Arosio B, Coto E, De Deyn P, Del Zompo M, Mateo I, Boada M, Antunez C, Lopez-Arrieta J, Epelbaum J, Schjeide BM, Frank-Garcia A, Giedraitis V, Helisalmi S, Porcellini E, Pilotto A, Forti P, Ferri R, Delepine M, Zelenika D, Lathrop M, Scarpini E, Siciliano G, Solfrizzi V, Sorbi S, Spalletta G, Ravaglia G, Valdivieso F, Vepsäläinen S, Alvarez V, Bosco P, Mancuso M, Panza F, Nacmias B, Bossù P, Hanon O, Piccardi P, Annoni G, Mann D, Marambaud P, Seripa D, Galimberti D, Tanzi RE, Bertram L, Lendon C, Lannfelt L, Licastro F, Campion D, Pericak-Vance MA, Soininen H, Van Broeckhoven C, Alpérovitch A, Ruiz A, Kamboh MI, Amouyel P. The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study. J Alzheimer’s Dis 2010; 22(1): 247-55

 

Lambert JC, Grenier-Boley B, Chouraki V, Heath S, Zelenika D, Fievet N, Hannequin D, Pasquier F, Hanon O, Brice A, Epelbaum J, Berr C, Dartigues JF, Tzourio C, Campion D, Lathrop M, Amouyel P. Implication of the immune system in Alzheimer's disease: evidence from genome-wide pathway analysis.  J Alzheimers Dis 2010; 20(4):1107-18

 

Le Fur I, Laumet G, Richard F, Fiévet N, Berr C, Rouaud O, Delcourt C, Amouyel P, Lambert JC. Association study of the CFH Y402H polymorphism with Alzheimer’s disease. Neurobiol Aging 2010; 31:165-66.

 

Laumet G, Chouraki V, Grenier-Boley B, Legry V, Heath S, Zelenika D, Fievet N, Hannequin D, Delepine M, Pasquier F, Hanon O, Brice A, Epelbaum J, Berr C, Dartigues JF, Tzourio C, Campion D, Lathrop M, Bertram L, Amouyel P, Lambert JC. Systematic analysis of candidate genes for Alzheimer's disease in a French, genome-wide association study. J Alzheimers Dis 2010; 20(4): 1181-8

 

Plichart M, Barberger-Gateau P, Tzourio C, Amouyel P, Pérès K, Ritchie K, Jouven X, Ducimetière P, Empana JP. Disability and incident coronary heart disease in older community-dwelling adults: the Three-City Study. J Am Geriatr Soc2010; 58:636-42

 

Power T, Stewart R, Ancelin ML, Jaussent I, Malafosse A, Ritchie K. 5-HTTLPR genotype, stressful life events and late-life depression: No evidence of interaction in a French population. Neurobiology of Aging 2010;31:886-887;

 

Ritchie K, Artero S, Portet F, Brickman AM, Muraskin J, Beanino E, Ancelin ML, Carrière I. Caffeine, cognitive functioning and white matter lesions in the elderly: establishing causality from epidemiological evidence. J Alzheimer’s Disease 2010; 20:S161-S166.

 

Ritchie K* Carrière I*, Ritchie C, Berr C, Artero S, Ancelin ML. Can we design population prevention programs to reduce dementia incidence? Simulation of the impact of removal of specific risk factors. British Medical Journal 2010, Aug 5;341:c3885. doi: 10.1136/bmj.c3885. & Author replyEpub Sep 3.

 

Ritchie K, Ancelin ML, Beanino E, Portet., Brickman A, Dartigues JF, Tzourio C, Dupuy AM, Ritchie C, Berr C, Artero S. Retrospective identification and characterization of Mild Cognitive Impairment from a prospective population cohort. Am J Geriatric Psychiatry 2010, 18:692-700.

 

Scali J, Ryan J, Carrière I, Dartigues JF, Tavernier B, Ritchie K, Ancelin ML. A prospective study of hormone therapy and depression in community-dwelling elderly women: the three city study. J Clin Psychiatry  2010; 71:1673-9

 

Seshadri S, Fitzpatrick AL, Ikram MA, DeStefano AL, Gudnason V, Boada M, Bis JC, Smith AV, Carassquillo MM, Lambert JC, Harold D, Schrijvers EM, Ramirez-Lorca R, Debette S, Longstreth WT Jr, Janssens AC, Pankratz VS, Dartigues JF, Hollingworth P, Aspelund T, Hernandez I, Beiser A, Kuller LH, Koudstaal PJ, Dickson DW, Tzourio C, Abraham R, Antunez C, Du Y, Rotter JI, Aulchenko YS, Harris TB, Petersen RC, Berr C, Owen MJ, Lopez-Arrieta J, Varadarajan BN, Becker JT, Rivadeneira F, Nalls MA, Graff-Radford NR, Campion D, Auerbach S, Rice K, Hofman A, Jonsson PV, Schmidt H, Lathrop M, Mosley TH, Au R, Psaty BM, Uitterlinden AG, Farrer LA, Lumley T, Ruiz A, Williams J, Amouyel P, Younkin SG, Wolf PA, Launer LJ, Lopez OL, van Duijn CM, Breteler MM; CHARGE Consortium; GERAD1 Consortium; EADI1 Consortium. Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA 2010; 303(18): 1832-40

Soremekun M, Stewart R, Portet F, Artero S, Ancelin ML, Ritchie K. Neurological signs and late-life depressive symptoms in a community population: the ESPRIT study. Int J Geriatr Psychiatry. 2010 Jul;25(7):672-8.

 

Straczek C, Ducimetiere P, Barberger-Gateau P, Helmer C, Ritchie K, Jouven X, Carcaillon L, Amouyel P, Tzourio C, Empana JP. Higher level of systemic C-reactive protein is independently predictive of coronary heart disease in older community-dwelling adults: the three-city study. J Am Geriatr Soc 2010 ; 58(1):129-35

 

Zhu YC, Tzourio C, Soumaré A, Mazoyer B, Dufouil C, Chabriat H. Severity of dilated Virchow-Robin spaces is associated with age, blood pressure, and MRI markers of small vessel disease: a population-based study. Stroke 2010; 41(11): 2483-90.

 

Zhu YC, Dufouil C, Soumaré A, Mazoyer B, Chabriat H, Tzourio C. High Degree of Dilated Virchow-Robin Spaces on MRI is Associated with Increased Risk of Dementia. J Alzheimer’s Dis 2010 Aug 30. [Epub ahead of print]

2011Akbaraly TN, Ancelin ML, Jaussent I, Ritchie K, Barberger-Gateau P, Dufouil C, Kivimaki M, Berr C, Ritchie K. Metabolic syndrome and onset of depressive symptoms in the elderly. Diabetes Care, 2011, 34(4):904-9.

 

Allanore Y, Saad M, Philippe D, Avouac J, Distler JHW, Amouyel P, Matucci-Cerinic M, Riemekasten G, Airo P, Melchers I, Hachulla E, Daniele C, Hans-Erich W, Wipff J, Lambert J-C, Hunzelmann N, Tiev K, Caramaschi P, Diot E, Kowal-Bielecka O, Valentini G, Mouthon L, Laszlo C, Damjanov N, Salvi E, Conti C, Muller M, Muller-Ladner U, Riccieri O, Ruiz B, Cracowski J-L, Letenneur L, Dupuy A-M, Meyer O, Kahan A, Munnich A, Boileau C, Martinez M. Genomewide scan identifies TNIP1, PSOR1C1 and RHOB as novel risk loci for systemic sclerosis.Plos Genet., 2011;7:e1002091.

 

Ancelin ML*, Carrière I*, Helmer C, Rouaud O, Pasquier F, Berr C, Chaudieu I, Ritchie K. Steroid and nonsteroidal anti-inflammatory drugs, cognitive decline, and dementia.  Neurobiology of Aging, 2011, doi:10.1016/j.neurobiolaging.2011.09.038.

 

Artero S, Touchon J, Dupuy A-M, Malafosse A, RitchieK. War exposure, 5-HTTPLPR genotype and life-time risk of depression. British Journal of Psychiatry. 2011; 199:43-8.

Barberger-Gateau P, Samieri C, Féart C, Plourde M. Dietary omega 3 polyunsaturated fatty acids and Alzheimer's disease: interaction with apolipoprotein E genotype. Curr Alzheimer Res. 2011 Aug;8(5):479-91. Review


Breton G, Froissart M, Janus N, Launay-Vacher V, Berr C, Tzourio C, Helmer C, Stengel B. Inappropriate drug use and mortality in community-dwelling elderly with impaired kidney function- the Three-City population-based study. Nephrol Dial Transplant. 2011 Sep;26(9):2852-9.

 

Cacciolati C, Hanon O, Alpérovitch A, Dufouil C, Tzourio C. Masked hypertension in the elderly: cross-sectional analysis of a population-based sample. Am J Hypertens. 2011 Jun;24(6):674-80.

 

Capuron, L., S. Schroecksnadel, C. Féart, A. Aubert, D. Higueret, P. Barberger-Gateau, S. Layé and D. Fuchs. 2011.Chronic low-grade inflammation in elderly persons Is associated with altered tryptophan and tyrosine metabolism: role in neuropsychiatric symptoms. Biological Psychiatry, 70, 175-82.

 

Carcaillon L, Alhenc-Gelas M, Bejot Y, Spaft C, Ducimetière P, Ritchie K, Dartigues JF, Scarabin PY. Increased thrombin generation is associated with acute ischemic stroke but not with coronary heart disease in the elderly: the Three-City cohort study. Arterioscler Thromb Vasc Biol. 2011;31:1445-51.
 

Carrière I, Gutierrez LA, Pérès K, Berr C, Barberger-Gateau P, Ritchie K, Ancelin ML. Late life depression and incident activity limitations: influence of gender and symptom severity. Journal of Affective Disorders, 2011, 133:42-50.

 

Chaudieu I, Norton J, Ritchie K, Birmes P, Vaiva G, Ancelin ML. Long-term health consequences of exposure to trauma in general elderly population: The mediating role of reexperiencing posttraumatic symptoms. Journal of Clinical Psychiatry 2011, 72(7):929-935.

 

Cyprien F, Courtet P, Malafosse A, Maller J, Meslin C, Bonafé A, Le Bars E, Menjot de Champfleur N , Ritchie K, Artero S. Suicidal behavior is associated with reduced corpus callosum area.Biological Psychiatry. 2011; 70:320-326.

Danaei G, Finucane MM, Lin JK, Singh GM, Paciorek CJ, Cowan MJ, Farzadfar F, Stevens GA, Lim SS, Riley LM, Ezzati M; Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Blood Pressure). National, regional, and global trends in systolic blood pressure since 1980: systematic analysis of health examination surveys and epidemiological studies with 786 country-years and 5·4 million participants. Lancet. 2011 Feb 12;377(9765):568-77.

 

Delcourt C, Delyfer MN, Rougier MB, Amouyel P, Colin J, Le Goff M, Malet F, Dartigues JF, Lambert JC, Korobelnik JF. Associations of Complement Factor H and smoking with early age-related macular degeneration: the Alienor Study. IOVS 2011; 52: 5955-62. (the ALIENOR study is conducted in a sub-group of the 3C-Bordeaux cohort.)

 

Empana J, Tafflet M, Escolano S, Vergnaux A, Bineau S, Ruidavets J, Montaye M, Haas B, Czernichow S, Balkau B, Ducimetiere P. Predicting CHD risk in France: a pooled analysis of the D.E.S.I.R., Three City, PRIME, and SU.VI.MAX studies. Eur J Cardiovasc Prev Rehabil. 2011;18:175-85
 

Feart, C., M.J. Torres, C. Samieri, M.A. Jutand, E. Peuchant, A.P. Simopoulos and P. Barberger Gateau. 2011. Adherence to a Mediterranean Diet and plasma fatty acids: data from the Bordeaux sample of the Three-City study. Brit J Nutr, 106 (1), 149-58.

Féart C, Helmer C, Fleury H, Béjot Y, Ritchie K, Amouyel P, Schraen-Maschke S, Buée L, Lambert JC, Letenneur L, Dartigues JF. Association between IgM anti-herpes simplex virus and plasma amyloid-beta levels. PLoS One. 2011;6(12):e29480. Epub 2011 Dec 28

 

Féart, C., K. Pérès, C. Samieri, L. Letenneur, J.-F. Dartigues and P. Barberger-Gateau. 2011. Adherence to a Mediterranean diet and onset of disability in older persons. European Journal of Epidemiology, e pub, 1-10

 

Fornage M, Debette S, Bis JC, Schmidt H, Ikram MA, Dufouil C, Sigurdsson S,

Lumley T, DeStefano AL, Fazekas F, Vrooman HA, Shibata DK, Maillard P, Zijdenbos A, Smith AV, Gudnason H, de Boer R, Cushman M, Mazoyer B, Heiss G, Vernooij MW,Enzinger C, Glazer NL, Beiser A, Knopman DS, Cavalieri M, Niessen WJ, Harris TB, Petrovic K, Lopez OL, Au R, Lambert JC, Hofman A, Gottesman RF, Garcia M,Heckbert SR, Atwood LD, Catellier DJ, Uitterlinden AG, Yang Q, Smith NL, AspelundT, Romero JR, Rice K, Taylor KD, Nalls MA, Rotter JI, Sharrett R, van Duijn CM,Amouyel P, Wolf PA, Gudnason V, van der Lugt A, Boerwinkle E, Psaty BM, Seshadri S, Tzourio C, Breteler MM, Mosley TH, Schmidt R, Longstreth WT, DeCarli C, Launer LJ. Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium. Ann Neurol. 2011 Jun;69(6):928-39.

 

Genin E, Hannequin D, Wallon D, Sleegers K, Hiltunen M, Combarros O, Bullido MJ, Engelborghs S, De Deyn P, Berr C, Pasquier F, Dubois B, Tognoni G, Fievet N, Brouwers N, Bettens K, Arosio B, Coto E, Del Zompo M, Mateo I, Epelbaum J, Franck-Garcia A, Helisalmi S, Porcellini E, Pilotto A, Forti P, Ferri R, Scarpini E, Siciliano G, Solfrizzi V, Sorbi  S, Spalletta G, Valdivesio F, Vepsalainen S, Alvarez V, Bosco P, Mancuso M, Panza F, Nacmias B, Bossu P, Hanon O, Piccardi P, Annoni G, Seripa D, Galimberti D, Licastro F, Soininen H, Dartigues J-F, Kamboh MI, Van Broeckhoven C, Lambert J-C, Amouyel P, Campion D. APOE and Alzheimer’s disease : a major gene with semi-dominant inheritance. Mol Psychiatry, 2011;16:903-7.

 

Germain M, Saut N, Greliche N, Dina C, Lambert JC, Perret C, Cohen W, Oudot-Mellakh T, Antoni G, Alessi MC, Zelenika D, Cambien F, Tiret L, Bertrand M, Dupuy AM, Letenneur L, Lathrop M, Emmerich J, Amouyel P, Trégouët DA, Morange PE. Genetics of venous thrombosis: insights from a new genome wide association study. PLoS One. 2011;6(9):e25581.

 

Godin O, Tzourio C, Maillard P, Mazoyer B, Dufouil C. Antihypertensive treatment and change in blood pressure are associated with the progression of white matter lesion volumes: the Three-City (3C)-Dijon Magnetic Resonance Imaging Study. Circulation. 2011 Jan 25;123(3):266-73.

 

Grimaud O, Dufouil C, Alpérovitch A, Pico F, Ritchie K, Helmer C, Tzourio C,

Chauvin P. Incidence of ischaemic stroke according to income level among older people: the 3C study. Age Ageing. 2011 Jan;40(1):116-21.

 

Helmer C, Stengel B, Metzger M , Froissart M, Massy ZA, Tzourio C, Berr C, Dartigues JF. Chronic Kidney Disease, cognitive decline and incident dementia: the 3C study.  Neurology 2011; 77(23):2043-2051,

 

Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, Carrasquillo MM, Abraham R, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Jones N, Stretton A, Thomas C, Richards A, Ivanov D, Widdowson C, Chapman J, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Beaumont H, Warden D, Wilcock G, Love S, Kehoe PG, Hooper NM, Vardy ER, Hardy J, Mead S, Fox NC, Rossor M, Collinge J, Maier W, Jessen F, Rüther E, Schürmann B,Heun R, Kölsch H, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Gallacher J, Hüll M, Rujescu D, Giegling I, Goate AM,Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K,Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H,McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Pankratz VS, Sando SB, Aasly JO, Barcikowska M, Wszolek ZK, Dickson DW,Graff-Radford NR, Petersen RC; Alzheimer's Disease Neuroimaging Initiative, vanDuijn CM, Breteler MM, Ikram MA, DeStefano AL, Fitzpatrick AL, Lopez O, LaunerLJ, Seshadri S; CHARGE consortium, Berr C, Campion D, Epelbaum J, Dartigues JF,Tzourio C, Alpérovitch A, Lathrop M; EADI1 consortium, Feulner TM, Friedrich P,Riehle C, Krawczak M, Schreiber S, Mayhaus M, Nicolhaus S, Wagenpfeil S,Steinberg S, Stefansson H, Stefansson K, Snaedal J, Björnsson S, Jonsson PV,Chouraki V, Genier-Boley B, Hiltunen M, Soininen H, Combarros O, Zelenika D,Delepine M, Bullido MJ, Pasquier F, Mateo I, Frank-Garcia A, Porcellini E, Hanon O, Coto E, Alvarez V, Bosco P, Siciliano G, Mancuso M, Panza F, Solfrizzi V,Nacmias B, Sorbi S, Bossù P, Piccardi P, Arosio B, Annoni G, Seripa D, Pilotto A,Scarpini E, Galimberti D, Brice A, Hannequin D, Licastro F, Jones L, Holmans PA, Jonsson T, Riemenschneider M, Morgan K, Younkin SG, Owen MJ, O'Donovan M, Amouyel, P, Williams J. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet. 2011 May;43(5):429-35.

 

Hong MG, Alexeyenko A, Lambert JC, Amouyel P, Prince JA. Genome-wide pathway analysis implicates intracellular transmembrane protein transport in Alzheimer disease. J Hum Genet., 2010;55:707-9.

 

Jaussent I, Dauvilliers Y, Ancelin ML, Dartigues JF, Tavernier B, Touchon J, Ritchie K, Besset A. Insomnia Symptoms in Older Adults: Associated Factors and Gender Differences. Am J Geriatr Psychiatry 2011; 19:88-97
 

Jaussent I, Bouyer J, Ancelin ML, AkbaralyTN, Pérès K, Ritchie K, Besset A, Dauvilliers Y. Insomnia and daytime sleepiness are risk factors for depressive symptoms in the elderly. Sleep, 2011, 34(8):1103-10.

 

Lambert JC, Dallongeville J, Ellis KA, Schraen-Maschke S, Lui J, Laws S, Dumont J, Richard F, Cottel D, Berr C, Ames D, Masters CL, Rowe CC, Szoeke C, Tzourio C, Dartigues JF, Buée L, Martins R, Amouyel P. Association of plasma Aß peptides with blood pressure in the elderly. PLoS One. 2011 Apr 15;6(4):e18536.

 

Legeai C, Jouven X, Tafflet M, Dartigues J, Helmer C, Ritchie K, Amouyel P, Tzourio C, Ducimetière P, Empana J. Resting heart rate, mortality and future coronary heart disease in the elderly: the 3C study. Eur J Cardiovasc Prev Rehabil. 2011 Jun;18(3):488-97.

 

Lenoir H, Dufouil C, Auriacombe S, Lacombe JM, Dartigues JF, Ritchie K, Tzourio C. Depression history, depressive symptoms, and incident dementia: the 3C Study. J Alzheimers Dis. 2011;26(1):27-38.

 

Leone N, Courbon D, Berr C, Barberger-Gateau P, Tzourio C, Alpérovitch A, Zureik M. Abdominal obesity and late-onset asthma: cross-sectional and longitudinal results: the 3C Study. Obesity 2011 Oct 20. doi: 10.1038/oby.2011.308. [Epub ahead of print]

 

Merle B, Delyfer MN, Korobelnik JF, Rougier MB, Colin J, Malet F, Féart C, Le Goff M, Dartigues JF, Barberger-Gateau P, Delcourt C. Dietary omega 3 fatty acids and the risk for age-related maculopathy: the Alienor Study. IOVS 2011; 52: 6004-11. (the ALIENOR study is conducted in a sub-group of the 3C-Bordeaux cohort.)

 

Montlahuc C, Soumaré A, Dufouil C, Berr C, Dartigues JF, Poncet M, Tzourio C, Alpérovitch A. Self-rated health and risk of incident dementia: a community-based elderly cohort, the 3C study. Neurology 2011;77(15):1457-64.

 

Morange PE, Oudot-Mellakh T, Germain M, Saut n, Antoni G, Alessi MC, Bertrand M, Dupuy AM, Letenneur L, Lathrop M, Lopez LM, Lambert JC, Emmerich J, Amouyel P, Tregouet D. KNG1 Ile581Thr and susceptibility to venous thrombosis. Blood, 2011;117:3692-4.


Nalls MA, Plagnol V, Hernandez DG, Sharma M, Sheerin UM, Saad M, Simón-Sánchez J, Schulte C, Lesage S, Sveinbjörnsdóttir S, Arepalli S, Barker R, Ben-Shlomo Y, Berendse HW, Berg D, Bhatia K, de Bie RM, Biffi A, Bloem B, Bochdanovits Z, Bonin M, Bras JM, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen H, Chinnery PF, Chong S, Clarke CE, Cookson MR, Cooper M, Corvol JC, Counsell C, Damier P, Dartigues JF, Deloukas P, Deuschl G, Dexter DT, van Dijk KD, Dillman A, Durif F, Dürr A, Edkins S, Evans JR, Foltynie T, Gao J, Gardner M, Gibbs JR, Goate A, Gray E, Guerreiro R, Gústafsson Ó, Harris C, van Hilten JJ, Hofman A, Hollenbeck A, Hu M, Huang X, Huber H, Hudson G, Hunt SE, Huttenlocher J, Illig T, Jónsson PV, Lambert JC, Langford C, Lees A, Lichtner P, Limousin P, Lopez G, Lorenz D, McNeill A, Moorby C, Moore M, Morris HR, Morrison KE, Mudanohwo E, O'Sullivan S, Pearson J, Perlmutter JS, Pétursson H, Pollak P, Post B, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Sawcer S, Schapira A, Scheffer H, Shaw K, Shoulson I, Sidransky E, Smith C, Spencer CC, Stefánsson H, Steinberg S, Stockton JD, Strange A, Talbot K, Tanner CM, Tashakkori-Ghanbaria A, Tison F, Trabzuni D, Traynor BJ, Utterlinden AG, Velseboer D, Vidailhet M, Walker R, van de Warrenburg B, Wickremaratchi M, Williams N, Williams-Gray CH, Winder-Rhodes S, Stefánsson K, Martinez M, Hardy J, Heutink P, Brice A, Gasser T, Singleton AB, Wood NW. Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. Lancet, 2011, 19;377:641-9.          

 

Plagnol V, Nalls MA, Bras JM, Hernandez DG, Sharma M, Sheerin UM, Saad M, Simón-Sánchez J, Schulte C, Lesage S, Sveinbjörnsdóttir S, Amouyel P, Arepalli S, Band G, Barker RA, Bellinguez C, Ben-Shlomo Y, Berendse HW, Berg D, Bhatia K, de Bie RM, Biffi A, Bloem B, Bochdanovits Z, Bonin M, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen H, Chinnery PF, Chong S, Clarke CE, Cookson MR, Cooper JM, Corvol JC, Counsell C, Damier P, Dartigues JF, Deloukas P, Deuschl G, Dexter DT, van Dijk KD, Dillman A, Durif F, Dürr A, Edkins S, Evans JR, Foltynie T, Freeman C, Gao J, Gardner M, Gibbs JR, Goate A, Gray E, Guerreiro R, Gústafsson Ó, Harris C, Hellenthal G, van Hilten JJ, Hofman A, Hollenbeck A, Holton J, Hu M, Huang X, Huber H, Hudson G, Hunt SE, Huttenlocher J, Illig T, Jónsson PV, Langford C, Lees A, Lichtner P, Limousin P, Lopez G, Lorenz D, McNeill A, Moorby C, Moore M, Morris H, Morrison KE, Mudanohwo E, O'Sullivan SS, Pearson J, Pearson R, Perlmutter JS, Pétursson H, Pirinen M, Pollak P, Post B, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Sawcer S, Schapira A, Scheffer H, Shaw K, Shoulson I, Sidransky E, de Silva R, Smith C, Spencer CC, Stefánsson H, Steinberg S, Stockton JD, Strange A, Su Z, Talbot K, Tanner CM, Tashakkori-Ghanbaria A, Tison F, Trabzuni D, Traynor BJ, Uitterlinden AG, Vandrovcova J, Velseboer D, Vidailhet M, Vukcevic D, Walker R, van de Warrenburg B, Weale ME, Wickremaratchi M, Williams N, Williams-Gray CH, Winder-Rhodes S, Stefánsson K, Martinez M, Donnelly P, Singleton AB, Hardy J, Heutink P, Brice A, Gasser T, Wood NW. International Parkinson's Disease Genomics Consortium (IPDGC); Wellcome Trust Case Control Consortium 2 (WTCCC2). A two-stage meta-analysis identifies several new loci for Parkinson's disease. PLoS Genet. 2011 Jun;7(6):e1002142. Epub 2011 Jun 30.

Plichart M, Celermajer DS, Zureik M, Helmer C, Jouven X, Ritchie K, Tzourio C, Ducimetière P, Empana JP. Carotid intima-media thickness in plaque-free site, carotid plaques and coronary heart disease risk prediction in older adults. The Three-City Study. Atherosclerosis 2011; 219:917-24

 

Raffaitin C, Féart C, Le Goff M, Amieva H, Helmer C, Akbaraly TN, Tzourio C, Gin H, Barberger-Gateau P. Metabolic syndrome and cognitive decline in French elders: the Three-City Study. Neurology. 2011 Feb 8;76(6):518-25.

 

Ritchie K, Jaussent I, Stewart R, Dupuy AM, Courtet P, Malafosse A, Ancelin ML. Adverse childhood environment and late-life cognitive functioning. Int J Geriatr Psychiatry 2011; 26:503-510.

 

Ryan J, Scali J, Carrière I, Dartigues JF, Tzourio C, Scarabin PY, Ritchie K, Ancelin ML.Oestrogen receptor polymorphisms and late-life depression.British Journal of Psychiatry, 2011, 199:126-31.

 

Ryan J, Scali J, Carrière I, Scarabin PY, Ritchie K, Ancelin ML. Estrogen receptor gene variants are associated with anxiety disorders in older women. Psychoneuroendocrinology. 2011 Nov;36(10):1582-6.

 

Saad M, Lesage S, Saint-Pierre A, Corvol JC, Zelenika D, Lambert JC, Vidailhet M, Mellick GD, Lohmann E, Durif F, Pollak P, Damier P, Tison F, Silburn PA, Tzourio C, Forlani S, Loriot AM, Giroud M, Helmer C, Portet F, Amouyel P, Lathrop M, Elbaz A, Durr A, Martinez M, Brice A. Genome-wide association study confirms BST1 and suggest a locus on 12q24 as risk loci for Parkinson’s disease in the European population. Hum Mol Genet, 2011;20:615-27.

 

Samieri C, Féart C, Proust-Lima C, Peuchant E, Tzourio C, Stapf C, Berr C, Barberger-Gateau P. Olive oil consumption, plasma oleic acid, and stroke incidence: the Three-City Study.Neurology. 2011;77(5):418-25.

 

Samieri, C., C. Feart, C. Proust-Lima, E. Peuchant, J. Dartigues, H. Amieva and P. Barberger-Gateau. 2011. Omega-3 fatty acids and cognitive decline: modulation by ApoEepsilon4 allele and depression. Neurobiology of Aging, 32 (12), 2317.e13-22.

           

Stengel B, Metzger M, Froissart M, Rainfray M, Berr C, Tzourio C, Helmer C. Epidemiology and prognostic significance of chronic kidney disease in the elderly- the Three-City prospective cohort study. Nephrol Dial Transplant. 2011 Oct;26(10):3286-95.

 

Stewart R, Godin O, Crivello F, Maillard P, Mazoyer B, Tzourio C, Dufouil C. Longitudinal neuroimaging correlates of subjective memory impairment: 4-year prospective community study. Br J Psychiatry 2011;198(3):199-205.

 

Straczek C, M. Tafflet, P. Barberger-Gateau, M Bertrand, A.M.Dupuy, P. Ducimetière, JP. Empana. Do lipids and apolipoproteins predict coronary heart disease under statin and fibrate therapy in the primary prevention setting in community-dwelling elderly subjects? The 3C Study. Atherosclerosis 2011; 214:426-31.

 

Zhu YC, Dufouil C, Mazoyer B, Soumaré A, Ricolfi F, Tzourio C, Chabriat H. Frequency and location of dilated Virchow-Robin spaces in elderly people: a population-based 3D MR imaging study. Am J Neuroradiol. 2011; 32(4):709-13.

2012Avila-Funes JA, Carcaillon L, Helmer C, Carrière I, Ritchie K, Rouaud O, Tzourio C, Dartigues JF, Amieva H. Is frailty a prodromal stage of vascular dementia? Results from the three-city study. J Am Geriatr Soc. 2012 Sep;60(9):1708-12

 

Ancelin ML, Carrière I, Barberger-Gateau P, Auriacombe S, Rouaud O, Fourlanos S, Berr C, Dupuy AM, Ritchie K. Lipid lowering agents, cognitive decline, and dementia: the three-city study. J Alzheimers Dis. 2012;30(3):629-37.

 

Ancelin ML, Carrière I, Helmer C, Rouaud O, Pasquier F, Berr C, Chaudieu I, Ritchie K. Steroid and nonsteroidal anti-inflammatory drugs, cognitive decline, and dementia. Neurobiol Aging. 2012;33(9):2082-90. Epub 2011 Nov 8.

 

Bazin F, Noize P, Dartigues JF, Ritchie KA, Tavernier B, Moore N, Pariente A, Fourrier-Reglat A. Engagement in leisure activities and benzodiazepine use in a French community-dwelling elderly population. Int J Geriatr Psychiatry. 2012;27(7):716-721. Epub 2011 Aug 31

 

Bergua V, Meillon C, Potvin O, Bouisson J, Le Goff M, Rouaud O, Ritchie K, Dartigues JF, Amieva H. The STAI-Y trait scale: psychometric properties and normative data from a large population-based study of elderly people. Int Psychogeriatr. 2012 Jul;24(7):1163-71. Epub 2012 Mar 21.

 

Bis JC, DeCarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, DeStefano AL, Lambert JC, Jack CR Jr, Struchalin M, Stankovich J, Ibrahim-Verbaas CA, Fleischman D, Zijdenbos A, den Heijer T, Mazoyer B, Coker LH, Enzinger C, Danoy P, Amin N, Arfanakis K, van Buchem MA, de Bruijn RF, Beiser A, Dufouil C, Huang J, Cavalieri M, Thomson R, Niessen WJ, Chibnik LB, Gislason GK, Hofman A, Pikula A, Amouyel P, Freeman KB, Phan TG, Oostra BA, Stein JL, Medland SE, Vasquez AA, Hibar DP, Wright MJ, Franke B, Martin NG, Thompson PM; Enhancing Neuro Imaging Genetics through Meta-Analysis Consortium, Nalls MA, Uitterlinden AG, Au R, Elbaz A, Beare RJ, van Swieten JC, Lopez OL, Harris TB, Chouraki V, Breteler MM, De Jager PL, Becker JT, Vernooij MW, Knopman D, Fazekas F, Wolf PA, van der Lugt A, Gudnason V, Longstreth WT Jr, Brown MA, Bennett DA, van Duijn CM, Mosley TH, Schmidt R, Tzourio C, Launer LJ, Ikram MA, Seshadri S; Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. Common variants at 12q14 and 12q24 are associated with hippocampal volume.Nat Genet. 2012 Apr 15;44(5):545-51. doi: 10.1038/ng.2237

 

Blachier M, Dauvilliers Y, Jaussent I, Helmer C, Ritchie K, Jouven X, Tzourio C, Amouyel P, Besset A, Ducimetiere P, Empana JP. Excessive daytime sleepiness and vascular events: the Three City Study. Ann Neurol. 2012 May;71(5):661-7. Epub 2012 Jan 23.

 

Cacciolati C, Tzourio C, Dufouil C, Alpérovitch A, Hanon O. Feasibility of Home Blood Pressure Measurement in Elderly Individuals: Cross-Sectional Analysis of a Population-Based Sample. Am J Hypertens. 2012 Dec;25(12):1279-85. Epub 2012 Aug 16

 

Canonico M, Brailly-Tabard S, Gaussem P, Setiao J, Rouaud O, Ryan J, Carcaillon L, Guiochon-Mantel A, Scarabin PY. Endogenous oestradiol as a positive correlate of plasma fibrinogen among older postmenopausal women: a population-based study (the Three-City cohort study). Clin Endocrinol (Oxf). 2012;77(6):905-10

 

Chasman DI, Fuchsberger C, Pattaro C, Teumer A, Böger CA, Endlich K, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster MC, O'Seaghdha CM, Glazer N, Isaacs A, Liu CT, Smith AV, O'Connell JR, Struchalin M, Tanaka T, Li G, Johnson AD, Gierman HJ, Feitosa MF, Hwang SJ, Atkinson EJ, Lohman K, Cornelis MC, Johansson A, Tönjes A, Dehghan A, Lambert JC, Holliday EG, Sorice R, Kutalik Z, Lehtimäki T, Esko T, Deshmukh H, Ulivi S, Chu AY, Murgia F, Trompet S, Imboden M, Coassin S, Pistis G; CARDIoGRAM Consortium; ICBP Consortium; CARe Consortium; WTCCC2, Harris TB, Launer LJ, Aspelund T, Eiriksdottir G, Mitchell BD, Boerwinkle E, Schmidt H, Cavalieri M, Rao M, Hu F, Demirkan A, Oostra BA, de Andrade M, Turner ST, Ding J, Andrews JS, Freedman BI, Giulianini F, Koenig W, Illig T, Meisinger C, Gieger C, Zgaga L, Zemunik T, Boban M, Minelli C, Wheeler HE, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Nöthlings U, Jacobs G, Biffar R, Ernst F, Homuth G, Kroemer HK, Nauck M, Stracke S, Völker U, Völzke H, Kovacs P, Stumvoll M, Mägi R, Hofman A, Uitterlinden AG, Rivadeneira F, Aulchenko YS, Polasek O, Hastie N, Vitart V, Helmer C, Wang JJ, Stengel B, Ruggiero D, Bergmann S, Kähönen M, Viikari J, Nikopensius T, Province M, Ketkar S, Colhoun H, Doney A, Robino A, Krämer BK, Portas L, Ford I, Buckley BM, Adam M, Thun GA, Paulweber B, Haun M, Sala C, Mitchell P, Ciullo M, Kim SK, Vollenweider P, Raitakari O, Metspalu A, Palmer C, Gasparini P, Pirastu M, Jukema JW, Probst-Hensch NM, Kronenberg F, Toniolo D, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, Siscovick DS, van Duijn CM, Borecki IB, Kardia SL, Liu Y, Curhan GC, Rudan I, Gyllensten U, Wilson JF, Franke A, Pramstaller PP, Rettig R, Prokopenko I, Witteman J, Hayward C, Ridker PM, Parsa A, Bochud M, Heid IM, Kao WH, Fox CS, Köttgen A. Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Hum Mol Genet. 2012;21(24):5329-43. Epub 2012 Sep 8

 

Davydov DM, Stewart R, Ritchie K, Chaudieu I. Depressed mood and blood pressure: the moderating effect of situation-specific arousal levels. Int J Psychophysiol. 2012;85(2):212-23. Epub 2012 May 1 (cohorte esprit)

 

De Hollander EL, Bemelmans WJ, Boshuizen HC, Friedrich N, Wallaschofski H, Guallar-Castillón P, Walter S, Zillikens MC, Rosengren A, Lissner L, Bassett JK, Giles GG, Orsini N, Heim N, Visser M, de Groot LC; WC elderly collaborators. The association between waist circumference and risk of mortality considering body mass index in 65- to 74-year-olds: a meta-analysis of 29 cohorts involving more than 58 000 elderly persons. Int J Epidemiol. 2012 Jun;41(3):805-17. Epub 2012 Mar 31

 

Delcourt C, Delyfer MN, Rougier MB, Lambert JC, Amouyel P, Colin J, Malet F, Le Goff M, Dartigues JF, Korobelnik JF. ARMS2 A69S polymorphism and the risk for age-related maculopathy: the ALIENOR study. Arch Ophthalmol. 2012 Aug 1;130(8):1077-8

 

Dumurgier J, Crivello F, Mazoyer B, Ahmed I, Tavernier B, Grabli D, François C, Tzourio-Mazoyer N, Tzourio C, Elbaz A. MRI atrophy of the caudate nucleus and slower walking speed in the elderly. Neuroimage. 2012 Apr 2;60(2):871-8. Epub 2012 Jan 28

 

Feart C, Alles B, Merle B, Samieri C, Barberger-Gateau P. Adherence to a Mediterranean diet and energy, macro-, and micronutrient intakes in older persons. J Physiol Biochem. 2012;68(4):691-700. Epub 2012 Jul 4

 

Foubert-Samier A, Catheline G, Amieva H, Dilharreguy B, Helmer C, Allard M, Dartigues JF. Education, occupation, leisure activities, and brain reserve: a population-based study. Neurobiol Aging. 2012 Feb;33(2):423.e15-25.Epub 2010 Nov 12

 

Germain M, Saut N, Oudot-Mellakh T, Letenneur L, Dupuy AM, Bertrand M, Alessi MC, Lambert JC, Zelenika D, Emmerich J, Tiret L, Cambien F, Lathrop M, Amouyel P, Morange PE, Trégouët DA. Caution in interpreting results from imputation analysis when linkage disequilibrium extends over a large distance: a case study on venous thrombosis. PLoS One. 2012;7(6):e38538. Epub 2012 Jun 4

 

Glymour MM, Chêne G, Tzourio C, Dufouil C. Brain MRI markers and dropout in a longitudinal study of cognitive aging: The Three-City Dijon Study. Neurology. 2012 Sep 25;79(13):1340-8. Epub 2012 Sep 12.

 

Glymour MM, Tzourio C, Dufouil C. Is cognitive aging predicted by one's own or one's parents' educational level? results from the three-city study. Am J Epidemiol. 2012 Apr 15;175(8):750-9. Epub 2012 Apr 2.

 

Hamilton G, Killick R; Genetic and Environmental Risk for Alzheimer's Disease Consortium; Translational Genomics Research Institute Consortium, Lambert JC, Amouyel P; European Alzheimer Disease Initiative, Carrasquillo MM, Pankratz VS, Graff-Radford NR, Dickson DW, Petersen RC, Younkin SG, Powell JF, Wade-Martins R. Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus. Neurobiol Aging. 2012 Aug;33(8):1848.e1-13. Epub 2012 Mar 8.

 

Hong MG, Reynolds CA, Feldman AL, Kallin M, Lambert JC, Amouyel P, Ingelsson E, Pedersen NL, Prince JA. Genome-wide and gene-based association implicates FRMD6 in Alzheimer disease.Hum Mutat. 2012 Mar;33(3):521-9. Epub 2012 Jan 23

 

Jaussent I, Bouyer J, Ancelin ML, Berr C, Foubert-Samier A, Ritchie K, Ohayon MM, Besset A, Dauvilliers Y. Excessive Sleepiness is Predictive of Cognitive Decline in the Elderly. Sleep. 2012;35(9):1201-7.

 

Keller MF, Saad M, Bras J, Bettella F, Nicolaou N, Simón-Sánchez J, Mittag F, Büchel F, Sharma M, Gibbs JR, Schulte C, Moskvina V, Durr A, Holmans P, Kilarski LL, Guerreiro R, Hernandez DG, Brice A, Ylikotila P, Stefánsson H, Majamaa K, Morris HR, Williams N, Gasser T, Heutink P, Wood NW, Hardy J, Martinez M, Singleton AB, Nalls MA; International Parkinson's Disease Genomics Consortium (IPDGC); Wellcome Trust Case Control Consortium 2 (WTCCC2). Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease. Hum Mol Genet. 2012 Nov 15;21(22):4996-5009. Epub 2012 Aug 13.

 

Leone N, Courbon D, Berr C, Barberger-Gateau P, Tzourio C, Alpérovitch A, Zureik M. Abdominal obesity and late-onset asthma: cross-sectional and longitudinal results: the 3C study. Obesity (Silver Spring). 2012 Mar;20(3):628-35. Epub 2011 Oct 20

 

Manetti M, Allanore Y, Saad M, Fatini C, Cohignac V, Guiducci S, Romano E, Airó P, Caramaschi P, Tinazzi I, Riccieri V, Della Rossa A, Abbate R, Caporali R, Cuomo G, Valesini G, Dieudé P, Hachulla E, Cracowski JL, Tiev K, Letenneur L, Amouyel P, Lambert JC, Chiocchia G, Martinez M, Ibba-Manneschi L, Matucci-Cerinic M. Evidence for caveolin-1 as a new susceptibility gene regulating tissue fibrosis in systemic sclerosis. Ann Rheum Dis. 2012;71(6):1034-41. Epub 2012 Mar 8

 

Marti H, Carcaillon L, Chavance M. Multiple imputation for estimating hazard ratios and predictive abilities in case-cohort surveys. BMC Med Res Methodol. 2012;12:24. doi: 10.1186/1471-2288-12-24

 

Mittag F, Büchel F, Saad M, Jahn A, Schulte C, Bochdanovits Z, Simón-Sánchez J, Nalls MA, Keller M, Hernandez DG, Gibbs JR, Lesage S, Brice A, Heutink P, Martinez M, Wood NW, Hardy J, Singleton AB, Zell A, Gasser T, Sharma M; International Parkinson’s Disease Genomics Consortium. Use of support vector machines for disease risk prediction in genome-wide association studies: concerns and opportunities. Hum Mutat. 2012 Dec;33(12):1708-18. Epub 2012 Aug 3.

 

Noize P, Bazin F, Pariente A, Dufouil C, Ancelin ML, Helmer C, Moore N, Fourrier-Réglat A. Validity of chronic drug exposure presumed from repeated patient interviews varied according to drug class. J Clin Epidemiol. 2012;65(10):1061-8. doi: 10.1016/j.jclinepi.2012.04.009. Epub 2012 Jul 21.

 

Norton J, Ancelin ML, Stewart R, Berr C, Ritchie K, Carrière I. Anxiety symptoms and disorder predict activity limitations in the elderly. J Affect Disord. 2012 Dec 10;141(2-3):276-85. doi: 10.1016/j.jad.2012.04.002. Epub 2012 May 3.

 

Plichart M, Empana JP, Lambert JC, Amouyel P, Tiret L, Letenneur L, Berr C, Tzourio C, Ducimetière P. Single polymorphism nucleotide rs1333049 on chromosome 9p21 is associated with carotid plaques but not with common carotid intima-media thickness in older adults. A combined analysis of the Three-City and the EVA studies. Atherosclerosis. 2012 May;222(1):187-90. Epub 2012 Mar 3.

 

Portet F, Brickman AM, Stern Y, Scarmeas N, Muraskin J, Provenzano FA, Berr C, Bonafé A, Artero S, Ritchie K, Akbaraly TN. Metabolic syndrome and localization of white matter hyperintensities in the elderly population. Alzheimers Dement. 2012;8(5 Suppl):S88-95.e1. Epub 2012 Jun 6.

 

Pottier C, Hannequin D, Coutant S, Rovelet-Lecrux A, Wallon D, Rousseau S, Legallic S, Paquet C, Bombois S, Pariente J, Thomas-Anterion C, Michon A, Croisile B, Etcharry-Bouyx F, Berr C, Dartigues JF, Amouyel P, Dauchel H, Boutoleau-Bretonnière C, Thauvin C, Frebourg T, Lambert JC, Campion D; PHRC GMAJ Collaborators. High frequency of potentially pathogenic SORL1 mutations in autosomal dominant early-onset Alzheimer disease. Mol Psychiatry. 2012 Sep;17(9):875-9. Epub 2012 Apr 3

 

Rachas A, Raffaitin C, Barberger-Gateau P, Helmer C, Ritchie K, Tzourio C, Amouyel P, Ducimetière P, Empana JP. Clinical usefulness of the metabolic syndrome for the risk of coronary heart disease does not exceed the sum of its individual components in older men and women. The Three-City (3C) Study.

Heart. 2012 Apr;98(8):650-5.

 

Ritchie K, Jaussent I, Portet F, Courtet P, Malafosse A, Maller J, Meslin C, Bonafé A, Le Bars E, de Champfleur NM, Artero S, Ancelin ML. Depression in elderly persons subject to childhood maltreatment is not modulated by corpus callosum and hippocampal loss. J Affect Disord. 2012;141(2-3):294-9. Epub 2012 Apr 24.

 

Ryan J, Canonico M, Carcaillon L, Carrière I, Scali J, Dartigues JF, Dufouil C, Ritchie K, Scarabin PY, Ancelin ML. Hormone treatment, estrogen receptor polymorphisms and mortality: a prospective cohort study. PLoS One. 2012;7(3):e34112. Epub 2012 Mar 23.

 

Ryan J, Scali J, Carrière I, Peres K, Rouaud O, Scarabin PY, Ritchie K, Ancelin ML. Estrogen receptor alpha gene variants and major depressive episodes. J Affect Disord. 2012;136(3):1222-6. Epub 2011 Nov 3.

 

Samieri C, Maillard P, Crivello F, Proust-Lima C, Peuchant E, Helmer C, Amieva H, Allard M, Dartigues JF, Cunnane SC, Mazoyer BM, Barberger-Gateau P. Plasma long-chain omega-3 fatty acids and atrophy of the medial temporal lobe. Neurology. 2012 Aug 14;79(7):642-50. Epub 2012 Aug 1.

 

Satizabal CL, Zhu YC, Mazoyer B, Dufouil C, Tzourio C. Circulating IL-6 and CRP are associated with MRI findings in the elderly: the 3C-Dijon Study. Neurology. 2012 Mar 6;78(10):720-7. Epub 2012 Feb 22.

 

Scarabin-Carré V, Canonico M, Brailly-Tabard S, Trabado S, Ducimetière P, Giroud M, Ryan J, Helmer C, Plu-Bureau G, Guiochon-Mantel A, Scarabin PY. High level of plasma estradiol as a new predictor of ischemic arterial disease in older postmenopausal women: the three-city cohort study. J Am Heart Assoc. 2012;1(3):e001388. Epub 2012 Jun 22.

 

Sharma M, Ioannidis JP, Aasly JO, Annesi G, Brice A, Van Broeckhoven C, Bertram L, Bozi M, Crosiers D, Clarke C, Facheris M, Farrer M, Garraux G, Gispert S, Auburger G, Vilariño-Güell C, Hadjigeorgiou GM, Hicks AA, Hattori N, Jeon B, Lesage S, Lill CM, Lin JJ, Lynch T, Lichtner P, Lang AE, Mok V, Jasinska-Myga B, Mellick GD, Morrison KE, Opala G, Pramstaller PP, Pichler I, Park SS, Quattrone A, Rogaeva E, Ross OA, Stefanis L, Stockton JD, Satake W, Silburn PA, Theuns J, Tan EK, Toda T, Tomiyama H, Uitti RJ, Wirdefeldt K, Wszolek Z, Xiromerisiou G, Yueh KC, Zhao Y, Gasser T, Maraganore D, Krüger R; GEO-PD Consortium. Large-scale replication and heterogeneity in Parkinson disease genetic loci. Neurology. 2012 Aug 14;79(7):659-67. Epub 2012 Jul 11.

 

Soisson V, Brailly-Tabard S, Empana JP, Féart C, Ryan J, Bertrand M, Guiochon-Mantel A, Scarabin PY. Low plasma testosterone and elevated carotid intima-media thickness: importance of low-grade inflammation in elderly men. Atherosclerosis. 2012;223(1):244-9. Epub 2012 May 16

 

Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann Ø, Bernard M, Brown AA, Cannon DM, Chakravarty MM, Christoforou A, Domin M, Grimm O, Hollinshead M, Holmes AJ, Homuth G, Hottenga JJ, Langan C, Lopez LM, Hansell NK, Hwang KS, Kim S, Laje G, Lee PH, Liu X, Loth E, Lourdusamy A, Mattingsdal M, Mohnke S, Maniega SM, Nho K, Nugent AC, O'Brien C, Papmeyer M, Pütz B, Ramasamy A, Rasmussen J, Rijpkema M, Risacher SL, Roddey JC, Rose EJ, Ryten M, Shen L, Sprooten E, Strengman E, Teumer A, Trabzuni D, Turner J, van Eijk K, van Erp TG, van Tol MJ, Wittfeld K, Wolf C, Woudstra S, Aleman A, Alhusaini S, Almasy L, Binder EB, Brohawn DG, Cantor RM, Carless MA, Corvin A, Czisch M, Curran JE, Davies G, de Almeida MA, Delanty N, Depondt C, Duggirala R, Dyer TD, Erk S, Fagerness J, Fox PT, Freimer NB, Gill M, Göring HH, Hagler DJ, Hoehn D, Holsboer F, Hoogman M, Hosten N, Jahanshad N, Johnson MP, Kasperaviciute D, Kent JW Jr, Kochunov P, Lancaster JL, Lawrie SM, Liewald DC, Mandl R, Matarin M, Mattheisen M, Meisenzahl E, Melle I, Moses EK, Mühleisen TW, Nauck M, Nöthen MM, Olvera RL, Pandolfo M, Pike GB, Puls R, Reinvang I, Rentería ME, Rietschel M, Roffman JL, Royle NA, Rujescu D, Savitz J, Schnack HG, Schnell K, Seiferth N, Smith C, Steen VM, Valdés Hernández MC, Van den Heuvel M, van der Wee NJ, Van Haren NE, Veltman JA, Völzke H, Walker R, Westlye LT, Whelan CD, Agartz I, Boomsma DI, Cavalleri GL, Dale AM, Djurovic S, Drevets WC, Hagoort P, Hall J, Heinz A, Jack CR Jr, Foroud TM, Le Hellard S, Macciardi F, Montgomery GW, Poline JB, Porteous DJ, Sisodiya SM, Starr JM, Sussmann J, Toga AW, Veltman DJ, Walter H, Weiner MW; Alzheimer's Disease Neuroimaging Initiative; EPIGEN Consortium; IMAGEN Consortium; Saguenay Youth Study Group, Bis JC, Ikram MA, Smith AV, Gudnason V, Tzourio C, Vernooij MW, Launer LJ, DeCarli C, Seshadri S; Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium, Andreassen OA, Apostolova LG, Bastin ME, Blangero J, Brunner HG, Buckner RL, Cichon S, Coppola G, de Zubicaray GI, Deary IJ, Donohoe G, de Geus EJ, Espeseth T, Fernández G, Glahn DC, Grabe HJ, Hardy J, Hulshoff Pol HE, Jenkinson M, Kahn RS, McDonald C, McIntosh AM, McMahon FJ, McMahon KL, Meyer-Lindenberg A, Morris DW, Müller-Myhsok B, Nichols TE, Ophoff RA, Paus T, Pausova Z, Penninx BW, Potkin SG, Sämann PG, Saykin AJ, Schumann G, Smoller JW, Wardlaw JM, Weale ME, Martin NG, Franke B, Wright MJ, Thompson PM; Enhancing Neuro Imaging Genetics through Meta-Analysis Consortium. Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet. 2012 Apr 15;44(5):552-61. doi: 10.1038/ng.2250.

 

Tregouet DA, Sabater-Lleal M, Bruzelius M, Emmerich J, Amouyel P, Dartigues JF, Kieler H, Morange PE. Lack of association of non-synonymous FUT2 and ALPL polymorphisms with venous thrombosis. J Thromb Haemost. 2012 Aug;10(8):1693-5.

 

Zhu YC, Chabriat H, Godin O, Dufouil C, Rosand J, Greenberg SM, Smith EE, Tzourio C, Viswanathan A. Distribution of white matter hyperintensity in cerebral hemorrhage and healthy aging. J Neurol. 2012;259(3):530-6

2013Ancelin ML, Ripoche E, Dupuy AM, Barberger-Gateau P, Auriacombe S, Rouaud O, Berr C, Carrière I, Ritchie K. Sex differences in the associations between lipid levels and incident dementia. J Alzheimers Dis. 2013 Jan 1;34(2):519-28. doi: 10.3233/JAD-121228

 

Barberger-Gateau P, Lambert JC, Féart C, Pérès K, Ritchie K, Dartigues JF, Alpérovitch A. From genetics to dietetics: the contribution of epidemiology to understanding Alzheimer's disease. J Alzheimers Dis. 2013;33 Suppl 1:S457-63

 

Brisset M, Boutouyrie P, Pico F, Zhu Y, Zureik M, Schilling S, Dufouil C, Mazoyer B, Laurent S, Tzourio C, Debette S. Large-vessel correlates of cerebral small-vessel disease. Neurology. 2013 Feb 12;80(7):662-669. Epub 2013 Jan 23.

 

Cacciolati C, Tzourio C, Hanon O. Blood pressure variability in elderly persons with white-coat and masked hypertension compared to those with normotension and sustained hypertension. Am J Hypertens. 2013 Mar;26(3):367-72. Epub 2012 Dec 21

 

Cacciolati C, Hanon O, Dufouil C, Alpérovitch A, Tzourio C. Categories of hypertension in the elderly and their 1-year evolution. The Three-City Study. J Hypertens. 2013 Apr;31(4):680-9. doi: 10.1097/HJH.0b013e32835ee0ca

 

Cougnard-Grégoire A, Delyfer MN, Korobelnik JF, Rougier MB, Malet F, Le Goff M, Dartigues JF, Colin J, Barberger-Gateau P, Delcourt C. Long-Term Blood Pressure and Age-Related Macular Degeneration: The ALIENOR Study. Invest Ophthalmol Vis Sci. 2013;54(3):1905-12.

 

Gabelle A, Richard F, Gutierrez LA, Schraen S, Delva F, Rouaud O, Buée L, Dartigues JF, Touchon J, Lambert JC, Berr C. Plasma amyloid-β levels and prognosis in incident dementia cases of the 3-City Study. J Alzheimers Dis. 2013;33(2):381-91

 

Genziani M, Stewart R, Béjot Y, Amieva H, Artero S, Ritchie K. Subjective memory impairment, objective cognitive functioning and social activity in French older people: findings from the Three Cities study. Geriatr Gerontol Int. 2013 Jan;13(1):139-45. Epub 2012 Jun 7

 

Guerreiro R, Wojtas A, Bras J, Carrasquillo M, Rogaeva E, Majounie E, Cruchaga C, Sassi C, Kauwe JS, Younkin S, Hazrati L, Collinge J, Pocock J, Lashley T, Williams J, Lambert JC, Amouyel P, Goate A, Rademakers R, Morgan K, Powell J, St George-Hyslop P, Singleton A, Hardy J; Alzheimer Genetic Analysis Group. TREM2 variants in Alzheimer's disease. N Engl J Med. 2013 Jan 10;368(2):117-27. Epub 2012 Nov 14

 

Greliche N, Germain M, Lambert JC, Cohen W, Bertrand M, Dupuis AM, Letenneur L, Lathrop M, Amouyel P, Morange PE, Trégouët DA. A genome-wide search for common SNP x SNP interactions on the risk of venous thrombosis. BMC Med Genet. 2013;14:36. doi: 10.1186/1471-2350-14-36

 

Holmans P, Moskvina V, Jones L, Sharma M; International Parkinson's Disease Genomics Consortium, Vedernikov A, Buchel F, Sadd M, Bras JM, Bettella F, Nicolaou N, Simón-Sánchez J, Mittag F, Gibbs JR, Schulte C, Durr A, Guerreiro R, Hernandez D, Brice A, Stefánsson H, Majamaa K, Gasser T, Heutink P, Wood NW, Martinez M, Singleton AB, Nalls MA, Hardy J, Morris HR, Williams NM. A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease. Hum Mol Genet. 2013 Mar 1;22(5):1039-49. Epub 2012 Dec 7

 

Jaussent I, Empana JP, Ancelin ML, Besset A, Helmer C, Tzourio C, Ritchie K, Bouyer J, Dauvilliers Y. Insomnia, daytime sleepiness and cardio-cerebrovascular diseases in the elderly: a 6-year prospective study. PLoS One. 2013;8(2):e56048. Epub 2013 Feb 14

 

Lambert JC, Grenier-Boley B, Harold D, Zelenika D, Chouraki V, Kamatani Y, Sleegers K, Ikram MA, Hiltunen M, Reitz C, Mateo I, Feulner T, Bullido M, Galimberti D, Concari L, Alvarez V, Sims R, Gerrish A, Chapman J, Deniz-Naranjo C, Solfrizzi V, Sorbi S, Arosio B, Spalletta G, Siciliano G, Epelbaum J, Hannequin D, Dartigues JF, Tzourio C, Berr C, Schrijvers EM, Rogers R, Tosto G, Pasquier F, Bettens K, Van Cauwenberghe C, Fratiglioni L, Graff C, Delepine M, Ferri R, Reynolds CA, Lannfelt L, Ingelsson M, Prince JA, Chillotti C, Pilotto A, Seripa D, Boland A, Mancuso M, Bossù P, Annoni G, Nacmias B, Bosco P, Panza F, Sanchez-Garcia F, Del Zompo M, Coto E, Owen M, O'Donovan M, Valdivieso F, Caffarra P, Scarpini E, Combarros O, Buée L, Campion D, Soininen H, Breteler M, Riemenschneider M, Van Broeckhoven C, Alpérovitch A, Lathrop M, Trégouët DA, Williams J, Amouyel P. Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease. Mol Psychiatry. 2013 Apr;18(4):461-70. doi: 10.1038/mp.2012.14. Epub 2012 Mar 20.

 

Merle BM, Delyfer MN, Korobelnik JF, Rougier MB, Malet F, Féart C, Le Goff M, Peuchant E, Letenneur L, Dartigues JF, Colin J, Barberger-Gateau P, Delcourt C.

High Concentrations of Plasma n3 Fatty Acids Are Associated with Decreased Risk for Late Age-Related Macular Degeneration. J Nutr. 2013 Apr;143(4):505-11. Epub 2013 Feb 13.

 

Mortamais M, Reynes C, Brickman AM, Provenzano FA, Muraskin J, Portet F, Berr C, Touchon J, Bonafé A, le Bars E, Maller JJ, Meslin C, Sabatier R, Ritchie K, Artero S. Spatial distribution of cerebral white matter lesions predicts progression to mild cognitive impairment and dementia. PLoS One. 2013;8(2):e56972. Epub 2013 Feb 14. (cohorte esprit)

 

Mura T, Proust-Lima C, Akbaraly T, Amieva H, Tzourio C, Chevassus H, Picot MC, Jacqumin-Gadda H, Berr C. Chronic use of benzodiazepines and latent cognitive decline in the elderly: Results from the Three-city study. Eur Neuropsychopharmacol. 2013 Mar;23(3):212-23. Epub 2012 Jun 15

 

Péquignot R, Tzourio C, Péres K, Ancellin ML, Perier MC, Ducimetière P, Empana JP. Depressive symptoms, antidepressants and disability and future coronary heart disease and stroke events in older adults: the Three City Study. Eur J Epidemiol. 2013 Mar;28(3):249-56. Epub 2013 Jan 22.

 

Ryan J, Carrière I, Carcaillon L, Dartigues JF, Auriacombe S, Rouaud O, Berr C, Ritchie K, Scarabin PY, Ancelin ML. Estrogen receptor polymorphisms and incident dementia: The prospective 3C study. Alzheimers Dement. 2013 Mar 9. doi:pii: S1552-5260(13)00011-3. 10.1016/j.jalz.2012.12.008. [Epub ahead of print]

 

Samieri C, Ginder Coupez V, Lorrain S, Letenneur L, Allès B, Féart C, Paineau D, Barberger-Gateau P. Nutrient patterns and risk of fracture in older subjects: results from the Three-City Study. Osteoporos Int. 2013 Apr;24(4):1295-305

 

Satizabal CL, Zhu YC, Dufouil C, Tzourio C. Inflammatory Proteins and the Severity of Dilated Virchow-Robin Spaces in the Elderly. J Alzheimers Dis. 2013;33(2):323-8